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Hyaloral® Plasma

Hyaloral® Plasma

Complementary feed that, when added to the regular diet, contributes to the development and maintenance of joints, tendons and ligaments, and to the pet’s overall immune response.

Species

Cat
Dog
Ferret
Rodent

Product description

  • Clinical evidence demonstrated in our own study with Hyaloral®1
  • Ingredients with clinical studies
  • Palatability tolerated satisfactorily in dogs with Hyaloral®2,3
  • Suitable modes of use according to the weight of the pet
  • Easily divisible tablet.

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Chicken protein-free
Chicken protein-free
No preservatives
No preservatives
No artificial colorings
No artificial colorings

Hyaloral® Plasma

Ingredients
Instructions for use
Indications
Benefits
Ingredients
Instructions
Indications
Benefits

Ingredients

Hyaluronic Acid4,5,6,7,8

Main component of synovial fluid in the joints, with viscoelastic and lubricating properties. Its oral intake helps facilitate joint movement due to its viscosity; protect cartilage from wear; reduce inflammation; and promote cartilage nutrition.

Hyaluronic Acid provides viscoelasticity to synovial fluid and is responsible for lubricating the synovial membrane and articular cartilage. Oral intake has been shown to be effective in osteoarthritis in dogs.

Hydrolyzed Enzymatically Collagen

Major component and structural basis of hyaline cartilage in the joints, the main tissue affected in joint degeneration processes. Hydrolyzed collagen is known to maintain cartilage integrity and provides flexibility, elasticity, and support. Its administration allows for greater absorption, distribution, and accumulation in articular cartilage.

Plasma proteins

Glucosamine

Amino sugar component of articular cartilage, substrate, and stimulator of the synthesis of chondroitin and hyaluronic acid. It protects hyaline cartilage from wear and promotes cartilage nutrition.

Chondroitin Sulfate

Main glycosaminoglycan of the extracellular matrix of cartilage. Nutrient that contributes to the formation of different components of cartilage, helps decrease cartilage destruction, and reduces inflammation by decreasing the action of proinflammatory molecules.

Gamma Oryzanol9,10,11

A naturally derived substance that exhibits powerful antioxidant action, helps eliminate free radicals, and reduces inflammation.

The combination of chondroitin sulfate, glucosamine, and antioxidants in the diet improves the condition of the joints and is effective for treating dogs with osteoarthritis.

Glucosamine and chondroitin have been shown to improve joint function and may be responsible for improving pain on manipulation, lameness, and range of motion.

Presentation

Hyaloral® Plasma

Box with 120 tablets of 4.5 g each, easily divisible to facilitate administration.

Hyaloral® Plasma

Box with 360 tablets of 4.5 g each, easily divisible to facilitate administration.

 

What are the instructions for use?

General

  • 1/4 tablet per 5 kg bodyweight/day.
  • From 40 kg bodyweight: 2 tablets per day in a single dose.

The tablet’s score line allows it to be split into 4 parts, so the dose can be adjusted to the pet’s weight.

It is recommended to mix with the regular food for a minimum of 3 months.

As this is a complementary feed, it can be given continuously.

How does arthritis affect our dogs?

Arthritis in dogs, small or large breeds, is a degenerative disease in which the joint is affected by inflammation and cartilage deterioration, causing pain and affecting the movement and quality of life of the animal. Usually caused by aging, injuries, or genetic predisposition.

Dogs with arthritis may suffer from muscle atrophy, pain, etc.

Muscle atrophy in animals involves a decrease in muscle size and strength. The animal loses muscle mass, causing a loss of functionality as well as making the affected area weaker.

 

How does this complementary feed help your pet’s joint health?

Complementary feed that, when added to the regular diet, contributes to the development and maintenance of joints, tendons and ligaments, and to the pet’s overall immune response.

 

Contributes to Healthy Development:

Hyaloral Gel for dogs and cats helps maintain the health of joints, tendons, cartilage, and ligaments, especially important in growing young animals.Hyaloral helps maintain the health of joints, tendons, cartilage, and ligaments, especially important in growing young animals.

 

Helps Maintain Mobility

Lubricates joints and flexibility, reducing stiffness in older animals.

 

Maintenance of Joint Health

Helps maintain joint health over time by helping prevent or delay joint problems.

 

Supports an Active Life

Facilitates an active life so your pets can enjoy physical activities such as playing, running, and jumping with greater comfort, contributing to their physical and emotional well-being.

 

Contributes to Healthy Development:

Hyaloral Gel for dogs and cats helps maintain the health of joints, tendons, cartilage, and ligaments, especially important in growing young animals.Hyaloral helps maintain the health of joints, tendons, cartilage, and ligaments, especially important in growing young animals.

 

Helps Maintain Mobility

Lubricates joints and flexibility, reducing stiffness in older animals.

 

Maintenance of Joint Health

Helps maintain joint health over time by helping prevent or delay joint problems.

 

Supports an Active Life

Facilitates an active life so your pets can enjoy physical activities such as playing, running, and jumping with greater comfort, contributing to their physical and emotional well-being.

 

Consult your veterinarian

At Pharmadiet, we encourage all pet owners to maintain a close relationship with their trusted veterinarian.

Regular consultations with veterinary professionals are fundamental for preventive care, early diagnosis of health problems, and planning appropriate treatments.

Through our close collaboration with these experts, we work together to keep your animal companions in their best health, ensuring a full and active life for them.

References

  1. Efficacy of an oral hyaluronate and collagen supplement as a preventive treatment of elbow dysplasia. Simón Martí-Angulo, Núria García-López, Ana Díaz-Ramos. J. Vet. Sci. (2014), 15(4), 569-574.
  2. Estudio palatabilidad gatos
  3.  Estudio palatabilidad perros
  4. Alves JC, Dos Santos AMMP, Jorge P, Lavrador CFTVB, Carreira LM. Effect of a single intra-articular high molecular weight hyaluronan in a naturally occurring canine osteoarthritis model: a randomized controlled trial. J Orthop Surg Res. 2021 May 3;16(1):290. doi: 10.1186/s13018-021-02423-4. PMID: 33941219; PMCID: PMC8091761.
  5. Alves et al. Effect of an oral joint suplement when compared to another in the management of hip osteoarthritis in working dogs. Topics in Compan An Med 32 (2017) 126-129.
  6. Bergin et al. Oral hyaluronan gel reduces post-operative tarsocrural effusion in the yearling Thoroghbred. Equine Vet J, 2006 38 (4): 375-378.
  7. Carmona et al. Efectos bioquímicos y Clínicos del hialuronato oral en Caballos andaluces jóvenes con osteocondrosis tarsocrural. Arch Med Vet, 2009, 41, 139-14
  8. Martello, E., Bigliati, M., Adami, R., Biasibetti, E., Bisanzio, D., Meineri, G., & Bruni, N. (2022). Efficacy of a dietary supplement in dogs with osteoarthritis: A randomized placebo-controlled, double-blind clinical trial. PloS one, 17(2), e0263971. https://doi.org/10.1371/journal.pone.0263971
  9. Minatel et al. Antioxidant activity of Ƴ-Oryzanol: a complex network of interactions.  Int J Mol Sci, 2016, 17, 1107.
  10. Parrado et al. Prevention of brain protein and lípid oxidation elicited by a water-soluble oryzanol enzymatic extract derived from rice bran. Eur J Nutr, 2003, 42: 307-314.
  11. Shin et al. Ƴ-Oryzanol supresses COX-2 expression by inhibiting reactive oxygen species-mediated Erk ½ and Egr-1 signaling in LPS-stimulated RAW264.7 macrophages. Biochem biophysic Research Communications, 2017, 491, 486-492.

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