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Hyaloral® Plasma Gel

Hyaloral® Plasma Gel

Complementary feed whose added nutrients to the usual diet contribute to the proper development and maintenance of joints, tendons, and ligaments, and to the pet’s overall immune response.

 

Species

Cat
Dog
Ferret
Rodent

Product description

Hyaloral® Plamsa Gel complementary feed with hydrolysed collagen, glucosamine, chondroitin sulfate, gamma oryzanol and hyaluronic acid, for dogs, cats, ferrets and rodents.

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Chicken protein-free
Chicken protein-free
No artificial colorings
No artificial colorings

Hyaloral® Plasma Gel

Ingredients
Instructions for use
Indications
Benefits
Ingredients
Instructions
Indications
Benefits

Ingredients

Hyaluronic Acid4,5,6,7,8

Main component of synovial fluid in the joints, with viscoelastic and lubricating properties. Its oral intake helps facilitate joint movement due to its viscosity; protect cartilage from wear; reduce inflammation; and promote cartilage nutrition.

Hyaluronic Acid provides viscoelasticity to synovial fluid and is responsible for lubricating the synovial membrane and articular cartilage. Oral intake has been shown to be effective in osteoarthritis in dogs.

 

Hydrolyzed Enzymatically Collagen

 

Major component and structural basis of hyaline cartilage in the joints, the main tissue affected in joint degeneration processes. Hydrolyzed collagen is known to maintain cartilage integrity and provides flexibility, elasticity, and support. Its administration allows for greater absorption, distribution, and accumulation in articular cartilage.

 

Plasma proteins

Glucosamine

 

Amino sugar component of articular cartilage, substrate, and stimulator of the synthesis of chondroitin and hyaluronic acid. It protects hyaline cartilage from wear and promotes cartilage nutrition.

 

Chondroitin Sulfate

 

Main glycosaminoglycan of the extracellular matrix of cartilage. Nutrient that contributes to the formation of different components of cartilage, helps decrease cartilage destruction, and reduces inflammation by decreasing the action of proinflammatory molecules.

 

Gamma Oryzanol9,10,11

Natural substance from rice bran, showing potent antioxidant action, helps eliminate free radicals, and reduce inflammation.

The combination of chondroitin sulfate, glucosamine, and antioxidants in the diet improves the condition of the joints and is effective for treating dogs with osteoarthritis.

Glucosamine and chondroitin have been shown to improve joint function and may be responsible for improving pain on manipulation, lameness, and range of motion.

Presentation

Hyaloral® Plasma Gel

Box with 50 mL container and dosing syringe. Oral gel.

 

Hyaloral® Plasma Gel

What are the instructions for use?

Cat

Oral administration.

  • For kittens: 1.5 ml per day.
  • For adult cats: 3 ml per day.

Dog

  • Up to 5 kg body weight: 1.5 ml per day.
  • From 5 to 10 kg body weight: 3 ml per day.

Ferret and roedent

  • 0.5 ml per kg body weight per day.

Other indications

Shake before use.

It is recommended to mix Hyaloral® Gel:

  • Into the daily diet of kittens and puppies from 3 months of age, for a minimum of 6 months.
  • Into the daily diet of adult animals for a minimum of 3 months.

As it is a complementary feed, it can be taken continuously.

How does arthritis affect our dogs or cats?

How does arthritis affect my pet?

 

Arthritis in dogs and cats is a degenerative disease in which the affected joint is affected by inflammation and deterioration of the articular cartilage, causing pain and difficulty in movement, affecting the quality of life of dogs and cats. Usually caused by aging, injuries, or genetic predisposition.

 

How does this complementary feed help your pet’s joint health?

This complementary feed for cats, dogs, and other species, which provides nutrients to aid in the proper development of joints, tendons, cartilage, and ligaments, and lubricates the joints.

 

Contributes to Healthy Development

Hyaloral Plasma Gel for dogs and cats helps maintain the health of joints, tendons, cartilage, and ligaments, especially important in growing young animals.Hyaloral helps maintain the health of joints, tendons, cartilage, and ligaments, especially important in growing young animals.

 

Helps Maintain Mobility

Lubricates joints and flexibility, reducing stiffness in older animals.

 

Maintenance of Joint Health

Helps maintain joint health over time by helping prevent or delay joint problems.

 

Contributes to Maintaining an Active Life

Facilitates an active life so your pets can enjoy physical activities such as playing, running, and jumping with greater comfort, contributing to their physical and emotional well-being.

 

Contributes to Healthy Development

Hyaloral Plasma Gel for dogs and cats helps maintain the health of joints, tendons, cartilage, and ligaments, especially important in growing young animals.Hyaloral helps maintain the health of joints, tendons, cartilage, and ligaments, especially important in growing young animals.

 

Helps Maintain Mobility

Lubricates joints and flexibility, reducing stiffness in older animals.

 

Maintenance of Joint Health

Helps maintain joint health over time by helping prevent or delay joint problems.

 

Contributes to Maintaining an Active Life

Facilitates an active life so your pets can enjoy physical activities such as playing, running, and jumping with greater comfort, contributing to their physical and emotional well-being.

 

Consult your veterinarian

At Pharmadiet, we encourage all pet owners to maintain a close relationship with their trusted veterinarian.

Regular consultations with veterinary professionals are fundamental for preventive care, early diagnosis of health problems, and planning appropriate treatments.

Through our close collaboration with these experts, we work together to keep your animal companions in their best health, ensuring a full and active life for them.

References

  1. Efficacy of an oral hyaluronate and collagen supplement as a preventive treatment of elbow dysplasia. Simón Martí-Angulo, Núria García-López, Ana Díaz-Ramos. J. Vet. Sci. (2014), 15(4), 569-574.
  2. Estudio palatabilidad gatos
  3.  Estudio palatabilidad perros
  4. Alves JC, Dos Santos AMMP, Jorge P, Lavrador CFTVB, Carreira LM. Effect of a single intra-articular high molecular weight hyaluronan in a naturally occurring canine osteoarthritis model: a randomized controlled trial. J Orthop Surg Res. 2021 May 3;16(1):290. doi: 10.1186/s13018-021-02423-4. PMID: 33941219; PMCID: PMC8091761.
  5. Alves et al. Effect of an oral joint suplement when compared to another products in the management of hip osteoarthritis in working dogs. Topics in Compan An Med 32 (2017) 126-129.
  6. Bergin et al. Oral hyaluronan gel reduces post-operative tarsocrural effusion in the yearling Thoroghbred. Equine Vet J, 2006 38 (4): 375-378.
  7. Carmona et al. Efectos bioquímicos y Clínicos del hialuronato oral en Caballos andaluces jóvenes con osteocondrosis tarsocrural. Arch Med Vet, 2009, 41, 139-14
  8. Martello, E., Bigliati, M., Adami, R., Biasibetti, E., Bisanzio, D., Meineri, G., & Bruni, N. (2022). Efficacy of a dietary supplement in dogs with osteoarthritis: A randomized placebo-controlled, double-blind clinical trial. PloS one, 17(2), e0263971. https://doi.org/10.1371/journal.pone.0263971
  9. Minatel et al. Antioxidant activity of Ƴ-Oryzanol: a complex network of interactions.  Int J Mol Sci, 2016, 17, 1107.
  10. Parrado et al. Prevention of brain protein and lípid oxidation elicited by a water-soluble oryzanol enzymatic extract derived from rice bran. Eur J Nutr, 2003, 42: 307-314.
  11. Shin et al. Ƴ-Oryzanol supresses COX-2 expression by inhibiting reactive oxygen species-mediated Erk ½ and Egr-1 signaling in LPS-stimulated RAW264.7 macrophages. Biochem biophysic Research Communications, 2017, 491, 486-492.

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