Pharmadiet

Urpro® Plus Gel

Complementary feed for dogs and cats based on nutrients that help the proper functioning of the entire urinary system, especially at the level of the lower urinary tract.

Species

Product description

  • Chicken protein-free
  • Preservative-free
  • Dosage adapted to the animal’s bodyweight
  • Shake before use

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Chicken protein-free
Chicken protein-free
Without preservatives.
Without preservatives.

Ingredients

Glucosamine

 

Cranberry Extract1,2,3

Contains hippuric acid and proanthocyanidins, which research suggests prevent bacteria, especially Escherichia coli, from adhering to the uroepithelial cells lining the bladder wall. Additionally, proanthocyanidins are known for their antioxidant and anti-inflammatory properties.

D-Mannose8

Prevents the adhesion of E. coli to urothelial receptors. Given that recurrent urinary tract infections (UTIs) are common in dogs and cats, preventive use of D-mannose in cases where infection is due to external factors is a valuable tool.

 

Horsetail (Equisetum arvense)4,5,6

 

 

Tryptophan

 

 

 

Chondroitin sulfate

Hyaluronic acid

Presentation

URPRO® Plus Gel

Box with 50 mL bottle and dosing syringe. Oral suspension.

 

URPRO® Plus Gel

What are the instructions for use?

General

Oral route.

Shake well before use.

Dog

1 mL / 5 kg bodyweight/day

Cat

1 mL / 5 kg bodyweight/day

Lower urinary tract disease (LUTD)

Lower Urinary Tract Disease (LUTD) encompasses a range of conditions affecting the lower urinary tract, including the bladder and urethra, and generates clinically similar symptoms in both dogs and cats.

Among the most common causes of LUTD are idiopathic cystitis in cats and bacterial infections in dogs. Obesity and stress represent primary risk factors that can increase susceptibility to urinary tract diseases in our pets. For prevention, especially in cats, promoting adequate water intake is recommended.

LUTD impacts the lower urinary tract in both dogs and cats. In dogs, urinary tract infections (UTIs) can have an incidence of up to 27%. Virtually all of these infections are caused by pathogenic bacteria ascending from the external genitals and the urethra, with E. coli being one of the most common culprits.

Feline idiopathic cystitis (FIC), also known as feline interstitial cystitis, is a relatively common disorder in veterinary practice. It can manifest as recurrent obstructive episodes, more common in males, or as non-obstructive episodes, which are common in young and female cats. Its origin is unknown in many cases and has been underdiagnosed to date due to a lack of etiopathogenic understanding or its similarity to other urinary syndromes.

How do the nutrients in the URPRO® Plus Gel complementary feed help pets?

URPRO® Plus Gel provides nutrients that support the proper functioning of the urinary system, especially at the level of the lower urinary tract.

 

The proper functioning of the urinary system

Especially at the level of the lower urinary tract.

 

The proper functioning of the urinary system

Especially at the level of the lower urinary tract.

 

Consult your veterinarian

At Pharmadiet, we encourage all pet owners to maintain a close relationship with their trusted veterinarian.

Regular consultations with veterinary professionals are fundamental for preventive care, early diagnosis of health problems, and planning appropriate treatments.

Through our close collaboration with these experts, we work together to keep your animal companions in their best health, ensuring a full and active life for them.

References

  1. Jepson, R. G., Williams, G., & Craig, J. C. (2012). Cranberries for preventing urinary tract infections. Cochrane Database Syst Rev, 10(10), CD001321. doi: 10.1002/14651858.CD001321.pub5.
  2. Chou, H. I., Chen, K. S., Wang, H. C., & Lee, W. M. (2016). Effects of cranberry extract on prevention of urinary tract infection in dogs and on adhesion of Escherichia coli to Madin-Darby canine kidney cells. Am J Vet Res, 77(4), 421-427. doi: 10.2460/ajvr.77.4.421.
  3. Carvajal-Campos, A., Jeusette, I., Mayot, G., Torre, C., André, A., & Di Martino, P. (2023). Adherence of Uropathogenic Escherichia Coli in Dog Urine After Consumption of Food Supplemented with Cranberry (Vaccinium Macrocarpon). J Vet Res, 67(1), 49-54. doi: 10.2478/jvetres-2023-0004.
  4. Bessa Pereira, C., Gomes, P. S., Costa-Rodrigues, J., Almeida Palmas, R., Vieira, L., Ferraz, M. P., Lopes, M. A., & Fernandes, M. H. (2012). Equisetum arvense hydromethanolic extracts in bone tissue regeneration: in vitro osteoblastic modulation and antibacterial activity. Cell Prolif, 45(4), 386-396. doi: 10.1111/j.1365-2184.2012.00826.x. Epub 2012 Jun 1.
  5. Cetojević-Simin, D. D., Canadanović-Brunet, J. M., Bogdanović, G. M., Djilas, S. M., Cetković, G. S., Tumbas, V. T., & Stojiljković, B. T. (2010). Antioxidative and antiproliferative activities of different horsetail (Equisetum arvense L.) extracts. J Med Food, 13(2), 452-459. doi: 10.1089/jmf.2008.0159.
  6. Gründemann, C., Lengen, K., Sauer, B., Garcia-Käufer, M., Zehl, M., & Huber, R. (2014). Equisetum arvense (common horsetail) modulates the function of inflammatory immunocompetent cells. BMC Complement Altern Med, 14:283. doi: 10.1186/1472-6882-14-283.
  7. Oliveira, C. ., & Granato, A. C. (2021). Research, Society and Development, 10(12), e501101220876. DOI: http://dx.doi.org/10.33448/rsd-v10i12.20876. (CC BY 4.0) | ISSN 2525-3409
  8. DeLomba, E. (2022). D-mannose Use for Bacterial Urinary Tract Infections in Dogs and Cats. AHVMA Journal, Volume 67, Summer Issue. Online Publication Date: 9 June 2022.

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